목적: Evidence has shown that multidisciplinary tumor board conferences (MTBCs) improve patient management for various cancer types. However, few retrospective studies have investigated MTBC efficacy for patients with gynecologic cancers. Here, we aimed to prospectively evaluate how MTBCs influence patient management in gynecologic oncology.
방법: This prospective study included 85 consecutive cases that were presented at gynecologic oncology weekly MTBCs of our tertiary university hospital between January 2015 and April 2016. The primary endpoint was treatment plan change rate, which included both major and minor changes. Major changes were defined as exchange, addition, or subtraction of treatment modality. Minor changes included all other, such as intramodality changes or treatment time changes. The secondary endpoints were the change rates of diagnosis, diagnostic work-up, and radiological and pathological findings.
결과: The overall change rate in treatment plan was 27.1%, which included 10.6% major changes and 16.5% minor changes. Among the treatment plan changes, change rate in treatment plan alone was 16.5%, and changes in diagnosis and radiological findings occurred in 7.1% and 3.5% of cases, respectively. Diagnosis and radiological findings were also changed in 9.4% and 10.6% of cases, respectively. However, there were no changes in pathological findings. Moreover, there was a change of diagnostic method for further work-up in 23.5% of cases.
결론: Gynecologic oncology MTBCs resulted in considerable changes in treatment plans. Diagnosis, diagnostic work-up, and radiological findings were also influenced by MTBCs. The data emphasizes the importance of a multidisciplinary team approach for gynecologic cancer management.