Potato tuber moth is one of invasive pests attacking potato cultivation around the world and its inhabitation has been changed due to climate change. It has caused nationwide damages in potato production in South Korea since it was introduced in 1968, suggesting the necessity for predicting its potential distribution to establish prevention and countermeasure of it. In this study, hence, we are to predict potential distribution of potato tuber moth in response to climate change. The main tool was CLIMEX software (CLIMEX version 4.0, Hearne software, Melbourne, Australia), implementing species distribution model and assessing species’ geographic suitability. To operate CLIMEX, model parameters were initially set up from biological information of potato tuber moth, and optimal parameter values were determined to have the best fit for the current worldwide distribution. After completing parameter estimation, the current climatic information and climate change scenario were inserted into CLIMEX to simulate the potential distribution of potato tuber moth. With the application of RCP 8.5 climate change scenario, climatic suitability of potato tuber moth in South Korea would be increased by time. Also, the highest Ecoclimatic Index (an index evaluating geographic suitability) was observed in Gyeongsang-do centered around Daegu.