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Highly sensitive electrochemical sensor for determination of ferulic acid based on the manganese dioxide nanoparticles-MWCNT nanocomposites
오철우 , 강성민 , ( A. T. Ezhil Vilian ) , 한영규 , 허윤석
UCI I410-ECN-0102-2018-500-003803834
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We prepared on an electrochemical sensor for the detection of ferulic acid (FA) that is based on a glassy carbon electrode modified with functional multiwalled carbon nanotubes that are decorated with MnO2 nanoparticles. The new electrode shows excellent electrochemical catalytic activity towards the oxidation of ferulic acid at pH7. Cyclic voltammetry reveals a 23mV decrease in the peak-to-peak separation of the oxidation and reduction waves. Under optimized conditions, the anodic peak current at a voltage of 150 mV (vs. Ag/AgCl) is linearly related to the peak current in the 0.082-220 μM concentration range, and the limit of detection (at an SNR of 3) is 10 nM. The sensor was applied to the determination of FA in spiked human serum samples and gave satisfactory results, with recoveries ranging from 97 to 99.2 %.

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