Tissue engineering can be one of essential keys that can provide a suitable resolutions to the problems relevant to skeletal diseases. In order to do so, it is desirable to develop artificial tissue scaffold that support filling up the damaged space and promoting tissue regeneration. Poly(L-lactic acid) (PLLA) is a synthetic polymer possessing biocompatibility and biodegradability. In this study, we used PLLA film of which surface was modified with multilayered CaP and hyaluronic acid (HA) coatings. The surface morphology, chemical components, chemical state, and hydrophilicity were evaluated using SEM, EDS, FTIR, and goniometer, respectively. HA and CaP coating promoted cell viability and differentiation, respectively. The proposed functionally enhanced PLLA can be applied in tissue engineering. ^** This research was supported by the Ministry of Trade, Industry and Energy(MOTIE), KOREA, through the Education Program for Creative and Industrial Convergence. (Grant Number N0000717).