One of the unique structural features of Mussel adhesive proteins (MAPs) is the presence of L-3,4-dihydroxyphenylalanine (DOPA) which is believed to be responsible for the adhesive characteristics of MAPs. We have tried the biomimetic chemical approach based on DOPA derivatives. The goal of this work is to incorporate functional DOPA derivatives chemically synthesized into a gel network by radical copolymerization and/or polyblending for developing a chemically synthesized underwater natural adhesives (UWA) with more practical application in adhesion property. We have developed the synthetic underwater bioadhesives through blending of the unoxidized DOPA derivatives containing acrylate groups or amino-sulfonate zwitterions and a triblock copolymer with metal ions for practical application to repair the adhesion strength under wet conditions. The incorporation of the DOPA has been successfully carried out and the analogues synthesized were characterized.