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A case of canalicular adenoma arising on the upper lip
( Seong Hoon Seo ) , ( Jong Hoon Kim ) , ( Mi Ryung Roh )
UCI I410-ECN-0102-2018-500-004089018
This article is 4 pages or less.

Canalicular adenoma is a rare benign tumor that arises in the minor salivary gland. A 71-year-old Korean male patient visited our clinic with a 1cm-sized asymptomatic nodule on the upper lip. Excision was performed under impression of epidermal cyst. Histopathologically, various sized tubular structures and squamous morules were seen. Tubular structures were lined with 1 or 2 layers of basophilic columnar cells. Immunohistochemical studies with S-100, CK(AE1/3) and p63 were positive. In conclusion, the case was diagnosed as canalicular adenoma. Clinically, canalicular adenoma usually presents as an asymptomatic nodule in the upper lip or buccal mucosa. Histopathologically, it shows tubular structures composed of 1 or 2 layers of columnar cells and intraluminal hemorrhage. Squamous morules, which seem to represent metaplasia, are known to be the unique finding for this tumor. Immunohistochemical stains are often helpful for the diagnosis of canalicular adenoma which is positive for S-100 and CK(AE1/3). We report an educational and rare case of canalicular adenoma in a Korean patient.

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