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Angiosarcoma of the scalp with delay in diagnosis
( Chung Hyeok Lee ) , ( Won-soo Lee )
UCI I410-ECN-0102-2018-500-004088480
This article is 4 pages or less.

A 77-year-old male patient presented with asymptomatic, solitary, 3*3 cm sized, round-shaped, erythematous plaque on the scalp for 3 months. There was ulcer in the center of the lesion, covered with a yellowish crust. The patient was diagnosed with lichen simplex chronicus and prurigo nodularis and was treated with oral antihistamine, topical steroid and steroid intralesional injection in local clinic 3 months ago. A biopsy was performed considering the possibilities of squamous cell carcinoma, keratoacanthoma and angiosarcoma. Histopathology showed anastomosing vascular structures with dense pleomorphic, atypical endothelial cell proliferation. Immunohistochemical staining revealed CD 31 positive endothelial cells in tumor. Finally, we diagnosed the patients with cutaneous angiosarcoma and referred to plastic surgery department for surgical treatment. Angiosarcomas are rare and highly fatal tumors derived from vascular endothelial cells. Because cutaneous angiosarcoma shares many clinical and histopathological features with other benign dermatosis, diagnosis of cutaneous angiosarcoma is often delayed. Thus, early diagnosis is most important to achieve the favorable prognosis. There are many clinical misdiagnoses because of delayed clinical suspicion and limitation of non-histological diagnostic tools. Therefore, if clinically suspicious lesion presents, biopsy and histologic confirmation should be performed.

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