Angioimmunoblastic T-cell lymphoma (AITL) is a subtype of peripheral CD4+ T-cell lymphoma. Skin lesions have been reported to occur in 40-50% of AITL cases, but it is difficult to doubt AITL with only cutaneous lesions because of its various and nonspecific cutaneous findings. A 58-year-old male, who was admitted in hemato-oncology department for generalized edema since 3 weeks ago, was consulted to our department for dermatologic evaluation. Physical examination showed asymptomatic, generalized erythematous maculopatches on trunk and extremities. He had no subjective symptom. He had medical history of alcoholic liver cirrhosis and rectal cancer. Skin biopsies revealed perifollicular and periadnexal lymphocytic infiltration in dermis and immunohistochemical stains were positive for CD3, CD4, CD8, CD20, PD-1 and 20% of Ki-67, and negative for Epstein-Barr virus encoded small RNAs in situ hybridization. Systemic evaluations were performed for the suspicion of AITL. Abdominal and pelvic computed tomography showed signs of local lymphatic metastasis. Positron emission tomography showed multiple metastatic lymphadenopathies and metastasis to appendix and pancreas. Omental, mesentary lymph node biopsies were also done, which revealed AITL. The patient underwent chemotherapy regimen for CHOP. We herein report a case of AITL which was initially diagnosed from skin biopsy to emphasize the importance of clinical suspicion in diagnosing lymphomas.