NTM refers to mycobacterium except for M. tuberculosis and leprosy bacteria. The prevalence of cutaneous NTM is increasing because of the illegal cosmetic procedure. We experienced cutaneous NTM patient who had received illegal botulinum toxin injection. A 68-year-old female patient visited our clinic with severe painful and itching skin lesion around chins three months ago. On the physical examination, several erythematous to brownish round shaped papules and nodules were observed. She had received botulinum toxin injection on both jaws illegally elsewhere 7 months previously. Upon histopathologic examination, inflammatory cell infiltration and palisading granulomatous inflammation were observed in the dermis. Initially, both mycobacterium tuberculosis (MTB) and non-tuberculous mycobacteria (NTM) were negative in polymerase chain reaction (PCR). In order to rule out the possibility of TB infection, TB-specific Ag induced IFN-gamma testing was performed. The result was positive and the patient was sent to the pulmonary medicine department but pulmonary TB was not suspected by chest high resolution computed tomography. Then, re-biopsy was subsequently performed to exclude cutaneous TB or NTM. From the histopathologic examination at re-biopsy, inflamed granulation with cavity formation was observed. MTB-PCR was negative, but NTM-PCR was positive. Finally, the patient was diagnosed with cutaneous NTM.