Calcinosis cutis is a term used to describe a group of disorders in which calcium deposits form in the skin. Insoluble compounds of calcium are deposited within the skin due to local or systemic factors. Calcinosis cutis is classified into 4 major types according to etiology: dystrophic, metastatic, iatrogenic, and idiopathic, and dystrophic calcinosis cutis is most common. The lesions usually appear as firm, whitish/yellowish papules, plaques or nodules on the surface of the skin. An 1y 6m-year-old male child presented with solitary yellowish papule on his left sole for 1 year. It was cyst like lesion and included serous discharge, developing gradually. Skin needle aspiration biopsy was done. Histologic examination revealed calcified deposits in subcutaneous fibrofatty tissue, findings consistent with a diagnosis of calcinosis cutis. After the biopsy, crusted plaque was removed and lesion was disappeared. Dystrophic Calcinosis cutis occurs in an area where there is damaged, inflamed, neoplastic or necrotic skin. This case’s patient had neonatal screening test on the lesion’s site at birth. We assumed that this test may be functioned to trauma at the site. There was a similar case that a 3-week-old male neonate with developing swelling on the right lower limb for which he was evaluated. Thus, dermatologists should be aware that calcinosis cutis may occur for various cause, and should perform biopsy to distinguish other dermatoses.