Reactive angioendotheliomatosis (RAE) is a rare benign angioproliferative condition of the skin. RAE manifests as diverse and nonspecific cutaneous lesions such as macules, papules, plaques and ulceration. Although the pathogenesis has not been fully elucidated, various diseases that cause vascular occlusion and hypoxemia are related to RAE. However, RAE after varicose vein surgery is rarely reported. A 26-year-old man visited our clinic with a 2-year history of painful skin lesions affecting the left lower limb. The lesions were poorly delimited, with deep purple colored plaques and macules. He had a varicose vein surgery by unlicensed non-medical personnel 5 years ago. Prominent proliferation of endothelial cells within the lumina of dermal vessels was observed in histologic examination. Immunohistochemistry showed that endothelial cells stained positively for CD31 and CD34. On the basis of the above findings, the patient was diagnosed with RAE. We referred the patient to rehabilitation center in order to alleviate the chronic leg edema worsening after varicose vein surgery.