Dermatofibroma (DF) is a common benign cutaneous neoplasm composed of fibrohistiocytic cells. Clinically, DF appears as asymptomatic, dome-shaped, erythematous to brownish nodule on the extremities or trunk. Several histopathological variants have been described, including cellular, hemosiderotic, atypical, epithelioid and deep DF. Hemosiderotic DF represents approximately 5% of DFs. It commonly presents as an asymptomatic, smooth surfaced, blue to grayish nodule. Histopathologically, hemosiderotic DF shows nonencapsulated dermal tumor composed of fibrohistiocytes, hemosiderin deposits, numerous small vessels and extravasated erythrocytes. It must be differentiated from melanoma and nonmelanocytic tumors, such as spitz nevus, dermal nevus and kaposi sarcoma. Treatment of choice is a surgical excision. A 38-year-old man presented with 1-year history of a 1.6 Ⅹ 1.4 cm sized brown to grayish smooth surfaced depressed patch on the left dorsum of hand. Histopathologically, punch biopsy specimen revealed dense fibrohistiocytic infiltrate, dilated blood vessels and hemosiderin deposition in the dermis. The patient was diagnosed with hemosiderotic dermatofibroma. Herein we report a rare case of hemosiderotic dermatofibroma on the left dorsum of hand.