Solid facial edema is a rarely described skin condition most commonly associated with acne vulgaris. The clinical presentation is localized symmetric non-pitting painless edema over the forehead, mid-face, nasolabial fold, and cheek. The pathogenesis is not well defined, making this condition difficult to treat. Recently, oral antibiotics, steroids, isotretinoin, and surgical procedures have been used. Despite various kinds of therapy, the effect is minimal and lesions persist in most cases. A 18-year-old man was referred to our department for diffuse swelling on his forehead and both cheeks persisting for 1 year. There was no history of drug hypersensitivity, food allergy, or similar complaints in his family. He had a medical history of acne. Routine laboratory tests including C1 esterase inhibitor level were within normal range. A skin biopsy taken from the cheek revealed dermal fibrosis and papillary dermal edema with inflammatory cells infiltration. Based on the patient’s clinicopathological correlation, we diagnosed solid facial edema. The patient was administered oral isotretinoin 20mg daily and methylprednisolone 8mg for 1week, 4mg for 1week and 2mg for 2weeks. After 6 months of therapy, the edema improved. Herein, we report a case of solid facial edema treated with isotretinoin and steroids.