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KCI 등재 SCOPUS
Diagnostics for the Cox model
( Yishu Xue ) , ( Elizabeth D. Schifano )
UCI I410-ECN-0102-2018-300-003888524
* 발행 기관의 요청으로 이용이 불가한 자료입니다.

The most popular regression model for the analysis of time-to-event data is the Cox proportional hazards model. While the model specifies a parametric relationship between the hazard function and the predictor vari-ables, there is no specification regarding the form of the baseline hazard function. A critical assumption of the Cox model, however, is the proportional hazards assumption: when the predictor variables do not vary over time, the hazard ratio comparing any two observations is constant with respect to time. Therefore, to perform cred-ible estimation and inference, one must first assess whether the proportional hazards assumption is reasonable. As with other regression techniques, it is also essential to examine whether appropriate functional forms of the predictor variables have been used, and whether there are any outlying or influential observations. This article reviews diagnostic methods for assessing goodness-of-fit for the Cox proportional hazards model. We illus-trate these methods with a case-study using available R functions, and provide complete R code for a simulated example as a supplement.

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