Purpose: The purpose of this study was to determine the effects of teaching communication training using Gagne’s 9 events of instruction and video clip on communication competency and interpersonal relations of nursing students. Methods: The participants were 79 nursing students (41 in the intervention group, 38 in the control group). A nonequivalent control group design was used. The research was carried out from September 7 to November 20, 2015. Teaching communication skills using Gagne’s 9 events of instruction and video clip were provided to the intervention group 180 minutes/session once a week for 9 weeks. Data were analyzed using chi-square test, independent t-test and ANCOVA with SPSS/PC version 21.0. Results: The intervention group reported significantly higher scores of communication competency(F=8.41, p=.005) and interpersonal relations(F=8.97 p=.004) compared to those of the control group at the completion of the intervention. Conclusion: The findings of this study show that Gagne’s 9 events of instruction and video clip is an effective communication training for improving communication competency and interpersonal relations in nursing students. A randomized clinical trial is needed to confirm the value of communication training using Gagne’s 9 events of instruction and video clip for nursing students.