An 80-year-old woman was referred for a skin colored dome shaped papule on the nose of 2 years duration. In polarized dermoscopy, the lesion was composed of large whitish globules. In the periphery, there were short telangiectatic vessels that were not arborizing. Histopathologic finding revealed variable-sized nodules of basaloid cells with peripheral palisading pattern and amorphous eosinophilic material in the center, and amyloid deposits were present in the stroma between clumps of tumor cells. Congo red stain showed these deposits as a reddish substance, and these depositions showed apple-green birefringence under polarized light, confirming the presence of amyloid. These findings suggested this tumor was nodular basal cell carcinoma (BCC) with amyloid deposition. The most common dermoscopic features of nodular BCC are irregular vascularity and translucency. Dermoscopic characteristics of macular amyloidosis are known as whitish or brownish central hub surrounded by various configurations of pigmentation. The central hub was replaced by a scarlike morphology in lichen amyloidosis, which can be similar to the characteristics of sebaceous gland origin tumor, molluscum contagiosum, and dermatofibroma does. In our case, it can be assumed that massive deposition of amyloid bodies presented as whitish globules on dermoscopy. Dermatologists should consider amyloid deposition can be manifested as whitish globules dermoscopically.