Background: It is not well known how effective chronic diseases are detected and followed up after general health examination. COPD prevalence by PFT in korea is about 13.4%, but only 2.1% patients have been diagnosed and treated. Aims: Thus, we evaluated outcomes of COPD patients coincidently detected by low dose CT for general health examination. Methods: We reviewed 5 year medical records from Korea University Guro Hospital who first diagnosed as lung cancer, COPD or angina after taking low dose CT and PFT for general health examination. We evaluated the following variables: age, gender, smoking history, follow up duration, dyspnea scale, chest CT findings, PFTs, and treatment. Results: Total 4809 patients had taken low dose CT in our hospital. Among them, only 9 patients were diagnosed as lung cancer, 57 patients diagnosed as COPD and 36 as angina. FEV1, smoking history, and amount of emphysema were well correlated each other. Most of COPD patients were lost and only 13 patients (23%) are being followed up. Coronary calcification was found in 36 patients and among them, 28 patients (78%) are being followed up with angina medical treatment. Conclusions: Low dose CT in health check-up center had low detection rate of lung cancer, COPD and angina. For COPD patients when compared to angina, loss rate was high because examination and explanation about COPD did not alert patients to follow up. Physicians should educate about the needs for proper management of COPD and its complications, because COPD is chronic disease that should be cared for life long like DM, HTN and angina.