Evaluation method of crude drug preparations was studied in Saengmaek-san. Zig-zag TLC scanning profiles and high performance liquid chromatograms were obtained from Saengmaek-san and its each crude drug. A method using TLC densitometry and high performance liquid chromatography was established for the precise determination of ginsenoside Rb₁ in Saengmaek-san containing Ginseng Radix. Consequently, ginsenoside Rb₁ content was 0.45-0.48 ㎎ per g of Saengmaek-san. This method was found to be useful for the quality evaluation of oriental medicinal preparations.