For the determination of aliphatic carbamates, the quantitative analysis of carisoprodol was investigated by gas chromatography (GC) and spectrophotometry. All the methods studied were found to be very quantitative. The minimum experimental amounts of GC method, spectrophotometric method I and II were approximately 10^(-9), 10^(-5) and 10^(-8) mole, respectively. The obtained results showed that GC method I was much more sensitive and rapid than spectrophotometric method II.