Objects : the relationship between the body changes in microgravity and Su-Seung-Hwa-Gang(body water rising and heat falling) in Korean medicine. Methods : research of papers about the body changes in microgravity and Su-Seung-Hwa-Gang in Korean medicine. Conclusions : In microgravity, there are changes in cardiovascular system and sympathetic nerve system(SNS). A change in the SNS during simulated microgravity could induce several physiological changes. It is associated with Su-Seung-Hwa-Gang in Korean medicine.