Pipethanate hydrochloride was microencapsulated with ethylcellulose 20 cps by polymeric deposition from cyclohexane by temperature change to give a finer product, with slower drug release, than that obtained with 10 cps grade of ethylcellulose using normal process. To obtain a fine well coated product, vigorous agitation and slow rate of cooling around the phase separation temperature were employed. The effect of core to wall ratio and release of the drug into an aqueous medium were studied. The release of the drug from microcapsules is a function of the drug to wall material ratio and the overall microcapsule size. The amount of the drug released(Q) is directly proportional to the square root of time. The release appears to proceed by a diffusion process. The release rate is also affected by the pH of the dissolution medium.