It is well known that lactobacillus products are a living bacterial preparation, which acts as the antibacterial and antidiarrhea agents. Beause of the specificity as the living bacterial preparation, this preparation should be remarkably considered to the stabilities in its manufacturing process and storage more than any others. In this report, it has been considered about its stabilities as the following items. 1) Selection of strains. 2) Control of seed strains. 3) Cultivation and its conditions. 4) Dry of microorganisms. 5) Manufacture of products. 6) Products storage. 7) Concerning to administration.