18.97.14.80
18.97.14.80
close menu
SCOPUS
정제류의 제제학적 연구 ; 경도 , 마손도 , 붕해시간 및 변동계수에 대하여
Pharmaceutical study on the Compressed Tablets ; Hardness , Friability , Disintegration time and Coefficient of Variance of Compressed tablets .
김수억 서성훈 이현우 ( Soo Uck Kim , Sung Hun Suh , Hyun U Lee )
약제학회지 vol. 2 iss. 2 218-233(16pages)
UCI I410-ECN-0102-2008-510-000821606

In order to know Hardness, Friability, Disintegration time and Coefficient of variance of the pharmaceutical tablets the 135 tablets sampled from market were tested in the paper. The samples tested in this paper were as follows; Antipyretics and Analgetics 41 Stomach and Digestives 22 Antituberculars 19 Vitamins 12 Sulfa drugs 9 Others (Antihistaminics etc) 32 Total 135 The results of the investigation are shown in table 1-8, Fig 1-Fig 6. Mean values of Hardness, Friability, Disintegration time and Coefficient of variance in each pharmaceutical preparation are as follows. <도표> The following summeries might be shown; 1. Ranges of Hardness, Friability, Disintegration time and Coefficient of variance are respectively 1.6 to 5.38 ㎏, 0.37 to 0.82 %, 2 minut 19 second to 5 minut 28 second and 2.09 to 3.10%. 2. According to the results, it could be indicated that higher Hardness shows lower Friability. 3. Against the general conception between Hardness and Disintegration time, higher Hardness shows lower Disintegration time. 4. It seems that higher mean weight shows lower Coefficient variance.

[자료제공 : 네이버학술정보]
×