Chronic discoid lupus erythematosus (DLE) of the scalp is a common cause of cicatrical alopecia. DLE has been often resistant to the traditional therapy including antimalarial drug such as hydroxychloroquine, systemic steroid, intralesional triamcinolone injection and surgical excision. Fractional laser has been proven effective in treating various hair disorders. Fractional laser has therapeutic effect by creating microscopic thermal zones in the scalp. Eventually, wound healing process may promote anagen hair follicle induction or acceleration of hair cycle progress. A 41-year old male presented with 5-cm sized bald patch on the scalp. Laboratory examination showed positive anti-neutrophil and anti-double strand DNA antibody. With impression of discoid lupus erythematosus, we applied fractional laser and intralesional steroid injection for the alopecic patch and could note favorable response after the 6 sessions of treatment at 4 weeks interval. Herein, we suggest fractional laser as an alternative treatment modality for DLE-induced alopecia.