In atopic dermatitis (AD), food allergy sometimes occurs in same patients, about 10-20%. Most common allergic foods in children are egg, peanut and milk. Children often outgrow allergies to milk and egg. There are reports of success in several clinical trials of oral food allergen immunotherapy (OIT) for milk, egg and peanut. However, patients with high specific IgE levels to certain food are refractory to OIT. Combined with OIT, omalizumab has been used in peanut and milk allergy to reduce allergic reactions. Here we report a use of omalizumab in combination with OIT in 6 year-old boy with AD and an egg white allergy. He has AD since 2 years old and at first visit, the CAP-RAST test showed high level in egg white, milk and peanut (Class 5, 2 and 2). In food challenge test, only egg white allergy was diagnosed. He had no reaction when he ate milk or peanut. 4 years later, he underwent an egg OIT, but failed after given 0.2mg of powdered egg white. We decided to use omalizumab. After 4 consecutive monthly omalizumab (150mg) injections, specific IgE antibodies to milk and egg were slightly reduced but persistent elevated (Class 3 and 1). He underwent an egg OIT and failed again after given 0.4mg of powdered egg white. 3rd egg OIT will be planned after 4 more consecutive monthly omalizumab injections. Our case suggests omalizumab can also be considered as a combination therapy with egg OIT, not only milk and peanut OIT.