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Case series; Neonatal calcinosis cutis on foot, probably due to needle injury
( Seung Hwi Kwon ) , ( Jung Woo Lee ) , ( Jiehyun Jeon ) , ( Hae Jun Song ) , ( Chil Hwan Oh )
UCI I410-ECN-0102-2017-510-000081118
This article is 4 pages or less.

Dystrophic cutaneous calcinosis cutis is a most common type of calcinosis cutis. It may arise at previously damaged skin such as local injury. Two 1-year-old male patients visited our clinic for hard solitary papule on heel. They were both born at the 39 weeks of gestation by vaginal delivery. Their neonatal course were uneventful. Their calcium and phosphate levels were within normal range. They had a history of needle stick injury on their heel for blood sampling. Excision biopsy were done on their papules. Histopathological findings exhibited focal irregular calcification in the upper dermis, surrounded by inflammatory cells, consistent with calcinosis cutis. Dystrophic calcinosis cutis arises at previously damaged skin. The calcification is assumed to be due to the release of alkaline phosphatase from the damaged tissue. Released alkaline phosphatase induce an increase in local pH, favoring the precipitation of calcium salts. Calcium, phosphate serum levels show normal value. Histopathologically, Dystrophic calcinosis cutis show calcium deposits in epidermis and the dermis. A foreign body giant cell reaction with inflammation is often found around calcium deposits. Treatment is needed for cosmetical defects. Surgical excision is widely used. Because of its rare incidence, these cases are not well known to the dermatologists. Herein we report case series of neonatal calcinosis on foot with reviewing of literatures.

[자료제공 : 네이버학술정보]
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