Subcutaneous sarcoidosis is known to be a rare subtype of cutaneous sarcoidosis. It is highly prone to have systemic involvement, and oral corticosteroid is generally accepted as the first line therapy when the evidence of internal organ involvement is obvious. However, according to the chronic course of subcutaneous sarcoidosis and its tendency of frequent recurrence, adverse effects of prolonged use of systemic corticosteroid cannot be ignored. Also, systemic corticosteroid cannot be taken into consideration in some patients. In this case, tetracycline was used based on the fact that it is generally accepted as a safe and effective medication in treatment of broad spectrum of cutaneous disease, and its property of granuloma formation inhibition. It has been proven that minocycline is effective in treatment of sarcoidosis, but there have been only one case report about the efficacy of minocycline on the treatment of subcutaneous sarcoidosis, a rare subtype of sarcoidosis. Herein we report a rare and interesting case of cutaneous sarcoidosis, which showed a significant clinical improvement upon use of minocycline.