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Adverse Cardiovascular Events after a Venomous Snakebite in Korea
( Ho Chul Kwon ) , ( Yong Sung Cha ) , 김현 , 이강현 , 황성오 , 김오현
UCI I410-ECN-0102-2017-510-000089285
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Although cardiac involvement is an infrequently recognized manifestation of venomous snakebites, little is known of the adverse cardiovascular events (ACVEs) arising as a result of snakebite in Korea. Accordingly, we studied the prevalence of ACVEs associated with venomous snakebites in Korea. A retrospective review was conducted on 65 consecutive venomous snakebite cases diagnosed and treated at the emergency department (ED) of Wonju Severance Christian Hospital between May 2011 and October 2014. ACVEswere defined as the occurrence of at least one of the following: 1) myocardial injury, 2) shock, 3) ventricular dysrhythmia, or 4) cardiac arrest Nine (13.8%) of the 65 patients had ACVEs; myocardial injury (9 patients, 13.8%) included hs-TnI elevation (7 patients, 10.8%) orelectrocardiogram (ECG) determined ischemic change (2 patients, 3.1%), and shock (2 patient, 3.1%). Neither ventricular dysrhythmia nor cardiac arrest was observed. Underlying cardiac diseases were more common in the ACVEs group than in the non-ACVEs group (p=0.017). Regarding complications during hospitalization, 3 patients (5.4%) in the non-ACVEs group and 3 patients (33.3%) in the ACVEs group developed bleeding (p=0.031) Significant proportion of the patients with venomous snakebite is associated with occurrence of ACVEs. Patients with ACVEs had more underlying cardiac disease and bleeding complication.

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