Introduction: Valsalva maneuver has been known as an effective method to dilate internal jugular vein. However, this maneuver cannot be performed in many cases such as children or unconscious patients. The aim of this study is to evaluate the effectiveness of methods which is combination of Valsalva maneuver and proximal internal jugular vein compression. Material & Methods: Healthy adult volunteers was recruited among a tertiary hospital employees. Basic anatomic and physiologic data were collected. During the study, subjects lied as if they were undergoing IJV catheter insertion, in supine position with their necks turned to left by 30 degrees. The main outcome was cross-sectional area of the distal IJV measured by ultrasound in four stages. Results: A total of 41 volunteers were enrolled. Twenty seven (64.3%) were male with average age 28.4 yr (±2.97). Average height was 171.7 cm (±8.62) and average neck circumference was 35.3 cm (±3.82). The average CSA-IJV was 1.06 cm2 (±0.36) without any maneuver. It increased to 1.34 cm2 (±0.45) with Valsalva maneuver (p<0.001), to 1.26 cm2 (±0.41) with digital compression (p<0.001), and to 1.41 cm2 (±0.47) with two maneuvers together (p=0.01). Conclusion: Proximal compression of IJV dilated the IJV, and this could have positive effect on the success of IJC. The next clinical trial could be needed.