The main aim of this paper is to study the meanings and impacts of mass media and vision on salvation in Nathanael West``s Miss Lonelyhearts. The newspaper was one of the most representative forms of media in early American mass culture, as it provided the masses with useful information and shared various opinions. I examined the process of communication and the relationship between mass media, which is represented by the newspaper, and the masses. In the process, we realize it is the newspaper``s editor, Shrike, who symbolizes the mechanism of mass media or the culture industry, that exerts an influence on the correspondents or the masses, rather than the advice columnist, Miss Lonelyhearts. I also discussed Miss Lonelyhearts’s various responses or interpretations on suffering in reality, such as jokes, violence, sadistic compulsions and perverse sexuality, and how Miss Lonelyhearts’ Christ complex is a parody on religion. In the last scene, the absurd death of Miss Lonelyhearts paradoxically implies the ironic reality, or an illusion of his religious salvation for people who are suffering. (Namseoul University)