Since 1992 distance education (DE), especially e-learning, has found wider usage in the field of higher, formal and vocational education in Mongolia as available technologies, including the Internet, have greatly facilitated teaching and learning methods. In recent years some NGOs and higher education institutions have been collaborating with foreign partners in developing and delivering quality e-learning programmes in Mongolia. This paper will discuss how an NGO, Mongolian e-Knowledge (MeK) has assured the quality of its e-learning development and delivery. It will look at the MeK’s quality assurance (QA) mechanism, analyze various QA measures taken during the e-learning process, and discuss issues and challenges of QA in e-learning.