The purpose of the article is to address a new instructional approach to a complex engineering course. We design a novel instructional method that combines mobile technology, simulation program, collaborative teamwork, problem-solving process, and a variety of evaluation techniques. We suggested five instructional principles that might be required to change the fundamental educational process by which learning is done. The proposed instructional method is expected to aspire for new perspectives on complex learning environment. Nevertheless we solely began by the research on the development of students’ complex problem-solving performance in a complex engineering course, the new instructional method in the article can promote the adoption of new instructional methods and strategies across different knowledge domains. In addition, the instructional method can provide a valuable bridge to acquisition and transfer of problem solving, motivation, and meaning learning.