Hemangiomas are the most common benign tumors of the liver. They are generally asymptomatic, but giant hemangioma can lead to symptoms such as abdominal discomfort, bleeding, obstructive symptoms. Kasabach-Merritt syndrome is a rare but life threatening complication of hemangioma, which is characterized by consumptive coagulopathy with large vascular tumors. More than 80% of Kasabach-Merritt syndrome occur within the first year of life and associated with either kaposiform hemangioendothelioma or tufted angioma. However, there are a few reports of Kasabach-Merritt syndrome with giant hepatic hemangioma in adult. The most important treatment for this syndrome is removal oflarge vascular tumor by surgery or medical treatment, but, there are limitations of surgical treatment due to bleeding tendency or patient condition. We herein present a case of unresectable giant hepatic hemangioma with disseminated intravascular coagulopathy (DIC) The patient was a 60 year old woman who complained hematochezia, ecchymosis and abdominal distension. She refused every surgical management, therefore the patient was treated with systemic glucocorticoid and beta blocker. After two weeks of steroid therapy, she responded partially for the treatment.