Tuberculosis was a relatively common disease until the mid-20th century and remains one of the world’s deadliest communicable diseases. In 2013, an estimated 9.0 million people developed tuberculosis and 1.5 million died from the disease. Tuberculosis is slowly declining each year and it is estimated that 37 million lives were saved between 2000 and 2013 through effective diagnosis and treatment. However, the global rate of extrapulmonary tuberculosis, especially gastrointestinal tuberculosis, has recently increased. This condition is linked to acquired immune deficiency syndrome, increasing migration, and use of immunosuppressive agents. The symptoms and signs of gastrointestinal and peritoneal tuberculosis are nonspecific, and unless a high index of suspicion is maintained, the diagnosis can be missed or delayed resulting in increased morbidity and mortality. Careful diagnostic evaluation of extrapulmonary findings is needed if systemic disease is suspected in the setting of known pulmonary tuberculosis or if extrapulmonary disease is the initial presenting factor. A 45-year-old male patient presented to our hospital with general weakness. Abdominal computed tomography findings were suspicious for cecal cancer with peritoneal seeding. However, pathologic results eventually indicated tuberculous enteritis and peritonitis. Here, we report this case of gastrointestinal tuberculosis mimicking cecal cancer.