Medicinal Chemistry : COMMUNICATION ; Engineering of a lipid-polymer nanoarchitectural platform for highly effective combination therapy of doxorubicin and irinotecan

T. Ramasamy; H. B. Ruttala; S. K. Ku; J. Y. Choi; H. G. Choi; J. O. Kim; J. H. Kim; T. H. Tran; C. S. Yong

영남대학교 약품개발연구소 약품개발연구소 연구업적집 Medicinal Chemistry : COMMUNICATION ; Engineering of a lipid-polymer nanoarchitectural platform for highly effective combination therapy of doxorubicin and irinotecan

Medicinal Chemistry : COMMUNICATION ; Engineering of a lipid-polymer nanoarchitectural platform for highly effective combination therapy of doxorubicin and irinotecan

( T. Ramasamy ) , ( H. B. Ruttala ) , ( J. Y. Choi ) , ( T. H. Tran ) , ( J. H. Kim ) , ( S. K. Ku ) , ( H. G. Choi ) , ( C. S. Yong ) , ( J. O. Kim )

영남대학교 약품개발연구소 2015.09

약품개발연구소 연구업적집 25권 101-101(1pages)

UCI I410-ECN-0102-2016-510-000368914

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초록

We developed a highly stable lipid-polymer nanoarchitectural platform for effective combination therapy of doxorubicin and irinotecan in the polyelectrolyte complex nanoparticle core, followed by incorporation of the whole assembly into a lecithin bilayer. It shows great potential for the treatment of a broad range of cancers.

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