In this study, a practical method to establish effluent limitations for priority water pollutants (PWPs) from industrial facilities was developed. As a case study, we collected influent and effluent wastewater samples from a terminal disposal plant for wastewater in Ulsan, Korea. Five water quality parameters and 17 PWPs were analyzed, and their discharge loads to the terminal disposal plant were calculated. In addition, the treatment efficiencies of PWPs were estimated by measuring concentrations and flow rates using the direct calculation method and the Monte Carlo simulation. If treatment efficiencies of PWPs are higher than 20%, the effluent limitations for industrial facilities can be maintained or relaxed in comparison with the Ministry of Environment (MOE) limitations for terminal disposal plants. Furthermore, a range of effluent limitations for the industrial facilities with various operating conditions of the terminal disposal plant (0-100%) were suggested. The method for establishing PWP limitations developed in this study can be applied to any terminal disposal plants.