This study was conducted to develop an advanced chemical wastewater treatment technology using new coagulants extracted from vermiculite. In order to make an optimal vermiculite extract solution(VES) that includes various cations useful for coagulation, extraction experiments by sulfuric acid were carried out. The characteristic of VES as coagulants was evaluated and compared to the existing inorganic coagulants, alum and ferric chloride. According to the experimental results, the concentrations of Al^(3+), Fe^(3+), ㎎^(2+), and Si^(4+) cations in VES were increasing with the increase of particle sizes, sulfuric acid concentration below 10N, temperature up to 100℃. and agitation time. It is found that VES can be applicated to the treatment of alkaline wastewater without pH control, because VES has various cations to make a coagulation with suspended colloids in a diverse pH range. The SS and COD removal efficiencies from the tannery wastewater by the dose of 0.2g-vermiculite(23.8㎎-Al^(3+), 27.6㎎-Fe^(3+), 33.6㎎-㎎^(2+), 0.2㎎-Si^(4+))/ℓ VES were higher than 80% and 30%, respectively, and independent on pH values. Especially a high COD removal rate of 61% was shown at the dose of 0.6g-vermiculite (72㎎-Al^(4+), 82.8㎎- Fe^(3+), 100.8㎎-㎎^(2+) , 0.6㎎-Si^(4+))/ℓ VES. However dosage more than lg(78.9㎎- A1^(3+))/ℓ of alum or 0.5g(103.6㎎-Fe^(3+))/ℓ of ferric chloride was required to maintain SS removal rates higher than 80%. Alkalinity and pH in the reactor decreased with the dose of VES, for example pH value of tannery wastewater decreased to 8 at the dose of 0.4g- vermiculite(47.6㎎-Al^(3+), 55.6㎎-Fe^(3+), 67.6㎎-㎎^(2+), 0.4㎎-Si^(4+))/ℓ VES. Turbidity removal rates in the reactor were 91∼93% at the dose of 0.l∼0.3g/ℓ VES. Another advantage from the coagulation by VES is less sludge generation in comparison with other inorganic coagulants.