The sulfur removing capacities of various Zn-Ti based sorbents prepared by co-precipitation and physical mixing method were investigated in the presence of H2O at middle temperature conditions (sulfidation : 480oC, regeneration : 580oC). The capacity of the conventional ZT sorbent (Zn/Ti : 1.5) prepared by physical mixing method was decreased with the level of H2O concentration. The capacity of the modified sorbent, promoted with 25wt% of cobalt oxide (ZTC-25) was not affected by water vapor. But the sorbent is not economically competitive, because the cobalt was very expensive. So far, Zn-Ti based sorbents with nano particle size were prepared by co-precipitation method (ZT-cp, ZTC5-cp), and they showed excellent sulfur removing capacity during multiple cycle, and were not affected by the water vapor at middle temperature condition. These results were explained by the differences in structures and physical properties measured by X-ray diffraction, BET and TEM images before/after H2S reaction, which were deeply related with preparation methods.