Infantile myofibroma(IM) is a rare benign tumor, which have been reported only 4 cases in Korean dermatologic literature since 1994. It can present solitary or multiple nodules over the entire body with or without visceral involvement such as a bone, lung, heart, and GIT, so can cause symptoms like a severe respiratory distress, vomiting or diarrhea. Prognosis is generally excellent if only a solitary nodule or multiple nodules limited to the skin are seen due to a high rate of spontaneous regression. Differential diagnosis of IM includes vascular tumor such as congenital hemangioma(CH) and infantile hemangiopericytoma. The patient 1 was a 2-week-old female, presented a solitary child fist sized dull-red rubbery nodule with central black eschar and purulent discharge on the right thigh since birth. After doppler USG, we performed diagnostic and therapeutic excision under impression of congenital epidermal cyst, rhabdomyosarcoma or CH. The patient 2 was a 1-month-old male, presented with several non-tender bean to walnut-sized dusky red firm nodules and subcutaneous masses on the neck root, extremities and flank. A skin biopsy was performed to identify the lesion. In second patient, whole body contrast CT proved that there is no involvement of visceral organ. Biopsy from the both patients were consistent with IM. Interestingly, second patient shows a slow overall spontaneous regression without any treatment based on regular follow up.