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Poly-L-lactic acid injection-associated paraffinoma of lower eyelids clinically mimicking xanthelasma
( Min Woo Kim ) , ( Hyun Sun Park ) , ( Hyun Sun Yoon ) , ( Soyun Cho )
UCI I410-ECN-0102-2015-500-002012602
This article is 4 pages or less.

Injectable poly-L-lactic acid(PLLA) is world-famous filler used in lipoatrophy and facial rejuvenation because of its collagen neogenesis effect which leads to gradual volume restoration. Until recently, quite a number of unwanted adverse events of PLLA have been reported. During early days of its use, relatively high incidence of papules and nodules after injection was a leading problem. These days main problems after PLLA injection are late-onset complications which include nodule, granuloma, pseudoabscess, angioedema and skin induration and many reports about them have been published. However, to the best of our knowledge, paraffinoma as a complication of PLLA has never been reported. A 47-year-old woman presented with an eight-month history of yellowish plaques in both lower eyelids. She reported that she had undergone PLLA injection in both lower eyelids 2 years previously at an aesthetic clinic. We did laboratory tests and skin biopsy. Based on laboratory findings and histological features, we diagnosed the condition as paraffinoma. Physicians and dermatologists who practice aesthetic dermatology should be aware of delayed complications of PLLA injection including paraffinoma.

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