Purpose: The purpose of this study was to evaluate osseointegration after placement of a machined surface implant and particulated-dentin-coated implant in a canine model. Materials and Methods: Four dogs were randomly assigned to two groups, and each group was further divided into two subgroups 4 and 8 weeks after implantation. The implant was placed under different conditions. Group 1 included the machined surface implant and group 2 included the particulated-dentin-coated implant. Histologic sections and histomorphometric analysis were obtained 4 and 8 weeks after surgery. Results: Group 2 showed a higher bone-implant contact rate and bone formation rate than group 1 in the 8 week group. In group 2, the 8 week group revealed significant elevation of both bone-implant contact rate and new bone formation rate versus the 4 week group. Conclusion: According to these results, particulate-dentin-coated implants can provide satisfactory stability and increase the quantity and maturity of new bones in the later stages of implant placement.