닫기
18.97.14.88
18.97.14.88
close menu
POSTER PRESENTATION 2: Critical Care/Experimental Medicine : PS2-26 ; Clinical Significance of Peripheral Venous Oxygen Saturation in Patients with Severe Sepsis or Septic Shock after Initial Resuscitation
( Hea Jin Chung ) , ( Jae Hyuck Lee )
UCI I410-ECN-0102-2015-500-002060002
This article is 4 pages or less.
* This article is free of use.

To evaluate the clinical significance of SpvO2 and to compare the correlation and agreement between SpvO2 and ScvO2 in severe sepsis or septic shock. It was a prospective observational study in patients who visited ED and diagnosed as severe sepsis or septic shock from Mar. 2009 to Sep. 2012. The outcome was 28-day mortality. The blood sample was obtained at initial and at 6 hr after initial resuscitation. From 380 eligible patients, 241 patients were included. The overall 28-day mortality was 17.0%. Baseline ScvO2 and SpvO2 values were not significantly different between survivors and nonsurvivors. After 6-hr management, SpvO2 were significantly lower in non-survivors than survivors. But, ScvO2 was not significantly different between groups. In survivor group, correlation between ScvO2 and SpvO2 was significant at initial and after 6-hour resuscitation (Spearman r = 0.290, p < 0.001; Spearman r = 0.307, p < 0.001, respectively). However, in non-survivor group, correlation was not significant (Spearman r = 0.172, p=0.315 at baseline; Spearman r = 0.136, p=0.397 at 6-hr resuscitation). Initial lactate values were significantly correlated with SpvO2 at baseline (Spearman r =-0.199, p=0.004) but not with ScvO2 (Spearman r =-0.054, p=0.445). After 6-hr resuscitation, blood lactate values were significantly correlated with SpvO2 but not with ScvO2 (lactate vs SpvO2, Pearson r=-0.437, p< 0.001; lactate vs ScvO2, Pearson r=-0.028, p=0.6934, respectively). Mortality rate was significantly higher in SpvO2 < 70% group than in SpvO2 >70% group without reference to ScvO2 values. And patients who had ScvO2>70% and SpvO2>70% were significantly higher survival times during 28-day follow-up period. Agreement between SpvO2 and ScvO2 was poor and SpvO2 was not correlated with ScvO2 especially in non-survivor group. However, SpvO2 values were significantly correlated with lactate values and the achievement of SpvO2 >70% during initial resuscitation showed significantly lower 28-day mortality without reference to ScvO2.

[자료제공 : 네이버학술정보]
×