Background: Alpha-Hydroxy acid (AHA) have recently been recognized as important adjunctive therapy in a variety of conditions including photodamage, actinic damage, melasma, hyperpigmentation disorders, acne, rosacea. Objectives: We examined whether there is an additional effect of physical application with water jet pressure compared to application of chemical peeing agent alone on facial skin. Methods: All subject’s face were randomly divided into test and control group. The test group was treated with chemical peeling combined physical effect with water jet pressure, and control group applied chemical peeling alone. The 23 healthy females aged between 22 and 39 were recruited, and we measured sebum output level by light transmission, pore area and number by fluorescent lighting, and comedone (whiteheads, blackheads) by lesion counting before treatment, and at 1, 2, 4 weeks after treatment. Results: Compared to before treatment, whiteheads and blackheads were significantly decreased at 1, 2 and 4 weeks in test group (p<0.05), but control group was showed a tendency to decrease at 1, 2 and 4 weeks. Pore area and number were significantly decreased at 1 week (p<0.05), and sebum output level was significantly decreased at 4 weeks (p<0.05) only in test group. Compared to control group, whiteheads and blackheads of test group were significantly decreased at 1 week. Conclusion: 4% AHA solution combined with physical effect had improving effects on whiteheads and blackheads synergistically.