Background: The relative frequency, clinical features, and survival outcomes of secondary cutaneous lymphoma remain poorly understood. Objectives: To determine the clinical characteristics and survival outcomes of secondary cutaneous lymphoma. Methods: The present retrospective cohort study included all 106 patients who presented with secondary cutaneous lymphoma. Patient medical records were reviewed to determine the clinical features, survival outcomes, and prognostic factors. Results: Secondary cutaneous lymphomas consisted of mature T-/NK-cell lymphomas (56%), mature B-cell lymphomas (35%), immature hematopoietic malignancies (8%), and Hodgkin lymphoma (1%). The lymphoma cell lineage did not significantly influence survival, even though T-/NK-cell lymphoma skin lesions were more extensive than B-cell lymphoma skin lesions. Prognostic factors that associated with poor survival were elevated lactate dehydrogenase at the time of initial staging, extranodal lymphoma, disseminated skin lesions, and an early (<6 months) development of skin lesions after the initial diagnosis. The two lymphoma cell lineages differed in terms of prognostic factors that influenced survival. Conclusion: Skin lesion characteristics such as time point of appearance and extent affect the survival outcomes of secondary cutaneous lymphoma. Cell lineage did not influence survival outcomes but the two lineages associated with different prognostic factors.