Background: Viral wart is a common disorder and conventional therapies are cryotherapy, CO2 laser ablation, bleomycin intralesional injection. Cryotherapy has been regarded as mainstay in treatment. However the cryotherapy causes unbearable pain and requires repeated treatment sessions during uncertain period.Objectives: The aim of this study was to evaluate the efficacy of punch excision prior to cryotherapy in viral wart treatment, as a synergistic method in reducing cryotherapy sessions. Methods: A retrospective chart and photographic review was performed on 39 patients with viral warts who received punch reduction prior to cryotherapy and compared with other patients who received only cryptherapy on similar site and size. Results: In 39 patients who received punch reduction, the average number of cryotherapy sessions after punch reduction was 1.1±2.57. Compared 15 patients who received punch reduction with other patients who received only cryotherapy, having similar size and site of wart, there was significant difference between them (p<0.01). Conclusion: Compared to ordinary treatment sessions of cryotherapy, punch reduction showed significant decrease in the duration of treatment. Punch excision may be an effective and synergistic method in reducing repeated cryptherapy sessions.