This study deals with English vocabulary learning by elementary school students and the development of vocabulary learning e-Book contents for use throughout Korea’s public school system from 2014. The existing researches on e-Book contents have focused on the development and application of e-Book contents. However, these earlier studies have been limited to offering suggestions such as hardware and software that could be developed for the future. This research is distinct from other studies in that it conducted an experimental class using vocabulary e-Book contents which contained pseudo words and looked at the effects of using e-Book contents. According to the results of the experimental study of this research, the developed e-Book contents helped improve receptive vocabulary through explicit learning in the areas of spelling, meaning, and related sentences. Also, it can be utilized effectively in improving productive vocabulary such as writing words. In conclusion, this study has shown that e-Book contents that will be developed in the future should include various types of multi-media elements such as still images, moving pictures, and sounds to captivate students’ interests and to motivate them.