Background/Aims: Migraine is frequently accompanied by symptoms consistent with functional gastrointestinal disor-ders (FGIDs). This study evaluated the prevalence of function-al gastrointestinal symptoms and assessed the symptoms` relationship with the concomitant functional symptoms of anxiety, depression, and headache-related disability. Meth-ods: This prospective study included 109 patients with mi-graine who were recruited from a headache clinic at a teach-ing hospital. The participants completed a self-administered survey that collected information on headache character-istics, functional gastrointestinal symptoms (using Rome III criteria to classify FGID), anxiety, depression, and headache-related disability. Results: In total, 71% of patients met the Rome III criteria for at least one FGID. In patients with FGID, irritable bowel syndrome was the most common symptom (40.4%), followed by nausea and vomiting syndrome (24.8%) and functional dyspepsia (23.9%). Depression and anxiety scores were significantly higher in patients meeting the cri-teria for any FGID. The number of the symptoms consistent with FGID in individual patients correlated positively with depression and anxiety. Conclusions: FGID symptoms de-fined by the Rome III criteria are highly prevalent in migraine. These symptoms correlate with psychological comorbidities, such as depression and anxiety. (Gut Liver 2013;7:668-674)