선암종에 비해 더욱 나쁜 예후로 알려진 역형성 췌장암과 관련된 증례로서, 영상 검사에서 처음에는 점액성 낭선암 진단 하에 수술을 진행하였으나, 병리 조직 검사 결과 각각의 낭종 모두에서 다형태 암종이 관찰되어 다발성 낭종을 형성하는 역형성 췌장암으로 진단한 1예를 보고하는 바이다.

Anaplastic carcinomas of the pancreas are rare pancreatic tumors, frequently showing various morphologies that include pleomorphic epithelial cells and relatively mononuclear spindle cell. Because they have highly aggressive nature and worse prognosis, it is important to recognize this disease entity. 68- year-old woman admitted for the treatment of epigastric pain and weight loss. Initial CT scan showed that 9 x 5.5 cm sized pancreatic cystic mass in tail and about 1.5 cm sized two cysts in head and neck. Because additional imaging study such as MRI and endoscopic ultrasonography showed large cystic mass had a possibility of malignant mucinous cystadenocarcinoma, we planned to distal pancreatectomy. However, frozen biopsy of each pancreatic cystic wall showed malignant pleomorphic cells, therefore, she underwent total pancreatectomy for the treatment of anaplastic carcinoma. Herein we reported a case of multifocal cyst forming anaplastic carcinoma of the pancreas.