Purpose: This study was to identify of the relationship of self-directed learning with job satisfaction and organizational commitment of nurses. Method: The subjects were 247 nurses who were working for the 5 of hospitals in Seoul, Daejeon and Kyong Ki. This study was conducted from Sep to Dec 2006. The data was collected by questionnaires and were analyzed using descriptive statistics, pearson correlation coefficients. Result: The self-directed learning was influenced significantly by the last school career, married state and job career. The job satisfaction was influenced significantly by job career. The organizational commitment was influenced significantly by age and job career. The self-directed learning is related with job satisfaction and organizational commitment of nurses. Conclusion: The findings indicated that the self-directed learning of nurses is important factor for improving job satisfaction and organizational commitment. Therefore it may be necessary further to develop the self-directed learning training program for efficiently nurse`s education.