This paper estimate and compare the regional index in China. Along with the economic development, many researcher interest the cultural factor. The cultural factor plays an important role in regional economic development. But the empirical research have some obstacles because of estimation limit. This paper try to estimate the regional cultural index in China, in the base of UNESCO, Canadian Statistics and New Zealand Statistics. Most of empirical study estimate each sector, and there are no one dimension index, this paper establish one dimension cultural index, include five first degree sector, the cultural supply, the cultural demand, the cultural support, the cultural heritage, the social and economic condition. And then this paper use AHP method calculate the sectoral weight, the cultural supply and the cultural support have higher weight, and another three sector have lower weight respectively. Each first degree sector include three second degree sector, so the cultural index have the fifteen second degree sector. This paper estimate the 31 regions cultural index, in 2001, and 2005-2009. The result finds that the regional cultural index have some disparity, and the average of cultural index increased by year. The result also finds that the cultural index and the regional economic development have strong relation, the regional economic development level more high, the cultural index also more high.